Pradaxa, INN- dabigatran etexilate

Pradaxa, INN: dabigatran etexilate mesilate

Dabigatran etexilate: An alternative to warfarin for patients with nonvalvular atrial fibrillation.

PURPOSE To critically appraise the evidence on dabigatran etexilate, Pradaxa, as an alternative to warfarin for stroke prevention among patients with nonvalvular atrial fibrillation. This information can assist nurse practitioners in making informed treatment decisions. DATA SOURCES A review of the literature was conducted using CINAHL and PubMed databases. Reports published on cardiovascular...

Early percutaneous pinning of hip fracture using propofol-ketamine-lidocaine admixture in a geriatric patient receiving dabigatran: a case report.

Hip fractures occur commonly in elderly patients. Many of these patients have multiple comorbidities requiring the use of anticoagulants. Some of the newer anticoagulants have no reliable method for reversal. This case report discusses the advantages and pitfalls of the selection of local anesthetic and monitored anesthesia care using a propofol-ketamine-lidocaine admixture for an elderly patie...

Something new under the sun? The Mediterranean diet and cardiovascular health.

1. Connolly SJ, Ezekowitz MD, Yusuf S, et al. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med 2009;361: 1139-51. [Erratum, N Engl J Med 2010;363: 1877.] 2. Weber JCP. Epidemiology of adverse reactions to nonsteroidal anti-inflammatory drugs. Adv Inflamm Res 1984;6:1-7. 3. FDA drug safety communication: safety review of post-market reports of serious bleeding events...

Practical management of bleeding due to the anticoagulants dabigatran, rivaroxaban, and apixaban.

The new oral anticoagulants dabigatran etexilate (Pradaxa), rivaroxaban (Xarelto), and apixaban (Eliquis) have predictable pharmacokinetic and pharmacodynamic profiles and are alternatives to warfarin. However, many physicians are wary of these drugs, since there is limited evidence on how to manage bleeding in patients taking them, and since no specific antidote is known to reverse their antic...